Found 106 matching trials
BEACON: A Study Evaluating the Safety and Efficacy of BEAM-101 in Patients With Severe Sickle Cell Disease PHASE1 This is an open-label, single-arm, multicenter, Phase 1/2 study evaluating ...
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University of Alabama at Birmingham
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Clinical Trial of the Dual Vector Base Editor for the Treatment of the CHD3-R1025W Mutation EARLY_PHASE1 To evaluate the safety, tolerability and preliminary efficacy study of a si...
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Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine
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CRISPR/cas13-medIated RNA TarGeting THerapy for the Treatment of Neovascular Age-related Macular Degeneration Investigator-initiated Trial (SIGHT-I) EARLY_PHASE1 Age-related macular degeneration (AMD) is a progressive disease leading to ...
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Eye & ENT Hospital of Fudan University
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Optimizing Cellular and Humoral Immunity by Vaccinating With PCV13 Before and After CAR-T Therapy PHASE2 The purpose of the study is to evaluate whether receiving the pneumococcal ...
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Moffitt Cancer Center
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Gene Editing as a Therapeutic Approach for Rett Syndrome N/A We designed the project to validate CRISPR/Cas9-based gene editing combined...
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University of Siena
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Study to Evaluate ACDN-01 in ABCA4-related Stargardt Retinopathy (STELLAR) PHASE1 This study is an open-label, single ascending dose clinical trial in partic...
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University of San Francisco
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Phase 1 Study to Evaluate Safety and Antiviral Activity of PBGENE-HBV in Adult Patients With Chronic Hepatitis B PHASE1 This is a Phase 1, open-label, dose escalation and dose expansion study to ...
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Massachusetts General Hospital/Harvard University
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A Clinical Study Exploring the Safety, Efficacy and Cell Metabolic Kinetics of Universal Car-t Cell Injection in CD19 and / or CD20 Positive Relapsed / Refractory B-cell Acute Lymphoblastic Leukemia in Adolescents, Children and Adults EARLY_PHASE1 This study is a single arm, open label, dose exploring clinical trial to ev...
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
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A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies PHASE1 This is an open-label, multicenter, Phase 1/2 study evaluating the safety a...
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University of Kansas
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Follow-up Study for Participants Jointstem Clinical Trial PHASE2 This study is a long term follow-up study to investigate the safety of auto...
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KyungHee University Gangdong Hospital
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